Hiring company: Takeda
Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Here, you will be a vital contributor to our inspiring, bold mission.
OBJECTIVES:
The new hire will be part of the bioanalytical group within the global DMPK department working at 35 Landsdowne St, Cambridge, MA. The requisition is for seeking a highly motivated, creative and productive individual with excellent knowledge and skills in mass spectrometry-based quantification of protein and other large molecule modalities in various biological matrices. The individual is expected to perform innovative method development for large molecule quantifications, effectively trouble-shoot bioanalytical assay related issues, and actively identify/adopt/develop new technologies to meet the ever-changing needs of projects together with key stakeholders such as DMPK project representatives, Drug Discovery Units (DDUs), DSRE and QTS groups. Hands on experience in applying various instrumental tools for bioanalysis, including but not limited to hybrid methods based on immunocapture, regular and micro/nano scale separation technologies, and triple quad (e.g. SCIEX 6500/ Thermo Altis) and high-resolution (e.g. Thermo Scientific Q-Exactive/Orbitrap Lumos/Eclipse) mass spectrometry-based assays.
ACOUNTABILITIES:
Serve as the lead bioanalytical scientist on projects or DMPK bioanalytical representative to interact with DMPK and Oncology DDU project members.
Support early drug discovery and translational research by providing high quality bioanalytical support with a focus on large molecule quantification especially mass spectrometry, and other pertinent platform technologies. Communicate with internal stakeholders regarding the assay needs, progress updates, and DMPK bioanalytical deliverables.
Apply independent creative thinking and lab work in seeking solutions for moving projects forward. Strong HPLC and mass spectrometry hardware skill is plus. Design, test, and implement new methodologies and processes that contribute to the research goals of the group/department.
Summarize and present the experimental result in the cross-functional project team, BA group and DMPK department meetings. Proactively seek for opportunities for updating professional skills through training or participating in conferences. Highly encouraged to contribute in external presentations and publications.
Provide scientific monitoring and guidance of external resources (CRO) for the method transfer, development, trouble shooting, qualification, validation and report to support drug discovery and nonclinical development programs. Assist in managing CRO sample and data flow logistics as necessary.
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
The applicant must have a Ph.D. in analytical chemistry in LC/MS or other related fields with 0-3 years of relevant industry research experience.
Hands-on experience and deep knowledge in the bioanalytical and biomarker assay development by triple quad are highly desirable. Prior experience in intact protein analysis and native MS by high-resolution mass spectrometry, immunoprecipitation, biological sample handling, or protein conjugation/purification is a strong plus.
She or he must demonstrate an excellent publication record in peer-reviewed journals as a lead author of a high level of creativity and problem-solving capabilities.
Must be detail oriented with excellent inter-personal skills and oral and written communication capabilities for working in a dynamic team environment and mentoring the junior scientist.
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
WHAT TAKEDA CAN OFFER YOU:
401(k) with company match and Annual Retirement Contribution Plan
Tuition reimbursement Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs
Empowering Our People to Shine
Discover more at takedajobs.com
No Phone Calls or Recruiters Please.
In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.
Effective November 1, 2021, absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. As of the same date, absent an approved religious or medical reason, US field-based employees, employees must be fully vaccinated in order to continue in their current roles. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. Candidates are encouraged to speak with their recruiter to seek further information on the applicable guidelines for the Business Unit/Function for which they have applied.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.